Howard N. Bockbrader: search on Z-Library

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1

A Comparison of the Pharmacokinetics and Pharmacodynamics of Pregabalin and Gabapentin

Dr Howard N. Bockbrader, David Wesche, Raymond Miller, Sunny Chapel, Nancy Janiczek, Paula Burger

Journal:

Clinical Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 167 KB

english, 2010

2

Population Pharmacokinetics of Pregabalin Extended‐Release in Healthy Volunteers and Patients With Postherpetic Neuralgia, Fibromyalgia, and Partial‐Onset Seizures

Chew, Marci, Ma, Guangli, Xie, Rujia, Bockbrader, Howard, Chapel, Sunny, Marshall, Scott

Journal:

Journal of Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 509 KB

english, 2019

3

Inter- and intra-subject variability in gabapentin absorption and absolute bioavailability

Barry E. Gidal, L.L. Radulovic, Sarah Kruger, Paul Rutecki, Michael Pitterle, Howard N. Bockbrader

Journal:

Epilepsy Research

Year:

2000

Language:

english

File:

PDF, 244 KB

english, 2000

4

Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine

Howard N. Bockbrader, Paula Burger, Lloyd Knapp

Journal:

Year:

2011

Language:

english

File:

PDF, 224 KB

english, 2011

5

Exposure-Response Analysis in Patients With Schizophrenia to Assess the Effect of Asenapine on QTc Prolongation

Chapel, Sunny, Hutmacher, Matt M., Haig, George, Bockbrader, Howard, de Greef, Rik, Preskorn, Sheldon H., Lalonde, Richard L.

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.07 MB

english, 2009

6

Relief of painful diabetic peripheral neuropathy with pregabalin: A randomized, placebo-controlled trial

Ralph W. Richter, Russell Portenoy, Uma Sharma, Linda Lamoreaux, Howard Bockbrader, Lloyd E. Knapp

Journal:

The Journal of Pain

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

7

Contrasting nutrient effects on the plasma levels of an amino acid-like antiepileptic agent from jejunal administration in dogs

Cheryl M. Stevenson, Louis L. Radulovic, Howard N. Bockbrader, David Fleisher

Journal:

Journal of Pharmaceutical Sciences

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

8

Asenapine Pharmacokinetics in Hepatic and Renal Impairment

Dr Pierre Peeters, Howard Bockbrader, Edwin Spaans, Peter Dogterom, Kenneth Lasseter, Thomas Marbury, Gordon L. Gibson, Rik de Greef

Journal:

Clinical Pharmacokinetics

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

9

Mucosal Uptake of Gabapentin (Neurontin) vs. Pregabalin in the Small Intestine

Nusara Piyapolrungroj, Cheng Li, Howard Bockbrader, Guangyu Liu, David Fleisher

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 174 KB

english, 2001

10

A Saturable Transport Mechanism in the Intestinal Absorption of Gabapentin Is the Underlying Cause of the Lack of Proportionality Between Increasing Dose and Drug Levels in Plasma

Barbra H. Stewart, Alan R. Kugler, Paul R. Thompson, Howard N. Bockbrader

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1006 KB

1993

11

Quantitative Whole-Body Autoradiographic Determination of Tacrine Tissue Distribution in Rats Following Intravenous or Oral Dose

William McNally, Michelle Roth, Remedios Young, Howard Bockbrader, Tsun Chang

Journal:

Pharmaceutical Research

Year:

1989

File:

PDF, 12.90 MB

1989

12

Safety and tolerability of CI-979 in patients with alzheimer's disease

John J. Sramek, Allen J. Sedman, Phillip A. Reece, Jameel Hourani, Howard Bockbrader, Neal R. Cutler

Journal:

Year:

1995

Language:

english

File:

PDF, 677 KB

english, 1995

13

Spectral analysis of the configuration and solution conformation of dihydrodigoxigenin epimers

Howard N. Bockbrader, Richard H. Reuning

Journal:

Journal of Pharmaceutical Sciences

Year:

1983

Language:

english

File:

PDF, 521 KB

english, 1983

14

High-performance liquid chromatographic analysis of cimetidine in serum and urine

David R.P. Guay, Howard N. Bockbrader, Gary R. Matzke

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1982

Language:

english

File:

PDF, 478 KB

english, 1982

15

Gabapentin to Pregabalin Therapy Transition

Bockbrader, Howard N., Budhwani, Meeta N., Wesche, David L.

Journal:

American Journal of Therapeutics

Year:

2013

Language:

english

File:

PDF, 475 KB

english, 2013

16

Effect of Cimetidine Administration on the Pharmacokinetics of Pirmenol

Stringer, Kathleen A., Lebsack, M. E., Cetnarowski-Cropp, Anne B., Goidfarb, Alien L., Raduiovic, Louis L., Bockbrader, Howard N., Chang, Tsun, Sedman, Allen J.

Journal:

Journal of Clinical Pharmacology

Year:

1992

Language:

english

File:

PDF, 480 KB

english, 1992

17

Impact of Population Pharmacokinetic-Pharmacodynamic Analyses on the Drug Development Process

Dr Stephen C. Olson, Howard Bockbrader, Rebecca A. Boyd, Jack Cook, Jeffrey R. Koup, Richard L. Lalonde, Paul H. Siedlik, J. Robert Powell

Journal:

Clinical Pharmacokinetics

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

18

Pregabalin Controlled-Release Pharmacokinetics in Healthy Volunteers: Analysis of Four Multiple-Dose Randomized Clinical Pharmacology Studies

Chew, Marci L., Alvey, Christine W., Plotka, Anna, Pitman, Verne W., Alebic-Kolbah, Tanja, Scavone, Joseph M., Bockbrader, Howard N.

Journal:

Clinical Drug Investigation

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

19

Tandem-in-Time Mass Spectrometry as a Quantitative Bioanalytical Tool

Rossi, David T., Hoffman, Keith L., Janiczek-Dolphin, Nancy, Bockbrader, Howard, Parker, Tresavon D.

Journal:

Analytical Chemistry

Year:

1997

Language:

english

File:

PDF, 270 KB

english, 1997

20

Population pharmacokinetics of gabapentin in infants and children

Danièle Ouellet, Howard N Bockbrader, David L Wesche, Douglas Y Shapiro, Elizabeth Garofalo

Journal:

Epilepsy Research

Year:

2001

Language:

english

File:

PDF, 284 KB

english, 2001

21

Population pharmacokinetics of pregabalin in healthy subjects and patients with chronic pain or partial seizures

Howard N. Bockbrader, Paula Burger, Lloyd Knapp, Brian W. Corrigan

Journal:

Year:

2011

Language:

english

File:

PDF, 501 KB

english, 2011

22

Population pharmacokinetics of pregabalin in healthy subjects and patients with post-herpetic neuralgia or diabetic peripheral neuropathy

Satoshi Shoji, Misaki Suzuki, Yoshiro Tomono, Howard N. Bockbrader, Shigeyuki Matsui

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 4.41 MB

english, 2011

23

Transport of Pregabalin in Rat Intestine and Caco-2 Monolayers

Nancy Jezyk, Cheng Li, Barbra H. Stewart, Xiaochun Wu, Howard N. Bockbrader, David Fleisher

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.29 MB

1999

24

Pharmacokinetics of gabapentin in subjects with various degrees of renal function

Blum, Robert A, Comstock, Thomas J, Sica, Domenic A, Schultz, Robert W, Keller, Erich, Reetze, Petra, Bockbrader, Howard, Tuerck, Deitrich, Busch, Janice A, Reece, Phillip A, Sedman, Allen J

Journal:

Clinical Pharmacology & Therapeutics

Year:

1994

Language:

english

File:

PDF, 427 KB

english, 1994

25

Identification of a pyridinium metabolite in human urine following a single oral dose of 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid monohydrochloride (CI-966), a .gamma.-aminobutyric acid uptake inhibitor

Radulovic, Louis, Woolf, Thomas, Bjorge, Susan, Taylor, Charles, Reily, Michael, Bockbrader, Howard, Chang, Tsun

Journal:

Chemical Research in Toxicology

Year:

1993

Language:

english

File:

PDF, 457 KB

english, 1993

26

Measurement of CI-979 (a candidate drug for the treatment of age-related disorders of cognition) in human plasma by capillary gas chromatography with nitrogen-selective detection

Barbara L. Windsor, Louis L. Radulovic, Howard N. Bockbrader, Tsun Chang

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1993

Language:

english

File:

PDF, 198 KB

english, 1993

27

Clinical Pharmacokinetics of Pregabalin in Healthy Volunteers

Bockbrader, Howard N., Radulovic, Louis L., Posvar, Edward L., Strand, James C., Alvey, Christine W., Busch, Janice A., Randinitis, Edward J., Corrigan, Brian W., Haig, George M., Boyd, Rebecca A., We

Journal:

Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 227 KB

english, 2010

28

Synthesis and metabolic profile of Cl-966: A potent, orally-active inhibitor of GABA uptake

Susan Bjorge, Ann Black, Howard Bockbrader, Tsun Chang, Vlad E. Gregor, Sandra J. Lobbestael, David Nugiel, Michael R. Pavia, Louis Radulovic, Thomas Woolf

Journal:

Drug Development Research

Year:

1990

Language:

english

File:

PDF, 250 KB

english, 1990

29

Stereoselective high-performance liquid chromatographic assay for pirmenol enantiomers in dog plasma

Nancy Janiczek, Howard N. Bockbrader, Tsun Chang, Gordon L. Amidon, David E. Smith

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1991

Language:

english

File:

PDF, 441 KB

english, 1991

30

Digoxin and metabolites in urine: A derivatization—high-performance liquid chromatographic method capable of quantitating individual epimers of dihydrodigoxin

Howard N. Bockbrader, Richard H. Reuning

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1984

Language:

english

File:

PDF, 792 KB

english, 1984

31

Effects of Age and Gender on Single-Dose Pharmacokinetics of Gabapentin

Rebecca A. Boyd, Dietrich Türck, Robert B. Abel, Allen J. Sedman, Howard N. Bockbrader

Journal:

Year:

1999

Language:

english

File:

PDF, 446 KB

english, 1999

32

Preclinical and Phase 1 clinical characterization of CI-979/ RU35926, a novel muscarinic agonist for the treatment of Alzheimer's disease

Allen J. Sedman, Howard Bockbrader, Roy D. Schwarz

Journal:

Year:

1995

Language:

english

File:

PDF, 445 KB

english, 1995

33

Safety, tolerability, and pharmacokinetics of pregabalin in children with refractory partial seizures: A phase 1, randomized controlled study

Mann, Donald, Liu, Jing, Chew, Marci L., Bockbrader, Howard, Alvey, Christine W., Zegarac, Elizabeth, Pellock, John, Pitman, Verne W.

Journal:

Year:

2014

Language:

english

File:

PDF, 482 KB

english, 2014

34

Gabapentin bioavailability: effect of dose and frequency of administration in adult patients with epilepsy

Barry E. Gidal, John DeCerce, Howard N. Bockbrader, Jose Gonzalez, Sarah Kruger, Michael E. Pitterle, Paul Rutecki, R.Eugene Ramsay

Journal:

Epilepsy Research

Year:

1998

Language:

english

File:

PDF, 119 KB

english, 1998

35

Pharmacokinetics, Mass Balance, and Induction Potential of a Novel GABA Uptake Inhibitor, CI-966 HC1, in Laboratory Animals

Louis L. Radulovic, Howard N. Bockbrader, Tsun Chang

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 750 KB

1993

36

Effect of the Gastrointestinal Prokinetic Agent Erythromycin on the Pharmacokinetics of Pregabalin Controlled-Release in Healthy Individuals: A Phase I, Randomized Crossover Trial

Chew, Marci L., Plotka, Anna, Alvey, Christine W., Pitman, Verne W., Alebic-Kolbah, Tanja, Scavone, Joseph M., Bockbrader, Howard N.

Journal:

Clinical Drug Investigation

Year:

2015

Language:

english

File:

PDF, 483 KB

english, 2015

37

Pregabalin Drug Interaction Studies: Lack of Effect on the Pharmacokinetics of Carbamazepine, Phenytoin, Lamotrigine, and Valproate in Patients with Partial Epilepsy

Martin J. Brodie, Elaine A. Wilson, David L. Wesche, Christine W. Alvey, Edward J. Randinitis, Edward L. Posvar, Neil J. Hounslow, Nicola J. Bron, G. L. Gibson, Howard N. Bockbrader

Journal:

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

38

Single-Dose Gabapentin Pharmacokinetics and Safety in Healthy Infants and Children

Haig, George M., Bockbrader, Howard N., Wesche, David L., Boellner, Samuel W., Ouellet, Daniele, Brown, Richard R., Randinitis, Edward J., Posvar, Edward L.

Journal:

Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

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